Mutational profiling can identify laryngeal dysplasia at risk of progression to invasive carcinoma

Early diagnosis of laryngeal squamous cell carcinoma (LSCC) at the stage of dysplasia could greatly improve the outcome of affected patients. For the first time we compared the mutational landscape of non-progressing dysplasia (NPD; n = 42) with progressing dysplasia (PD; n = 24), along with patient...

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Detalles Bibliográficos
Autores principales: Manterola, Lorea, Aguirre, Pablo, Larrea, Erika, Arestín, María, Gaafar, Ayman, Elorriaga, Kepa, Goicoechea, Ibai, Armesto, María, Fernández-Mercado, Marta, Zabalza, Ignacio, López-Duque, Juan Carlos, Larruskain, Ekhiñe, Sistiaga, Jon Alexander, Landa, Mikel, Zabala, Aitor, Santaolalla, Francisco, Municio, José Antonio, Ispizua, Ángel, García-Pedrero, Juana María, Rodrigo, Juan Pablo, Lawrie, Charles Henderson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919930/
https://www.ncbi.nlm.nih.gov/pubmed/29700339
http://dx.doi.org/10.1038/s41598-018-24780-7

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