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LH-21, A Peripheral Cannabinoid Receptor 1 Antagonist, Exerts Favorable Metabolic Modulation Including Antihypertensive Effect in KKAy Mice by Regulating Inflammatory Cytokines and Adipokines on Adipose Tissue

Patients with obesity are susceptible to hypertension and diabetes. Over-activation of cannabinoid receptor 1 (CB(1)R) in adipose tissue is proposed in the pathophysiology of metabolic disorders, which led to the metabolic dysfunction of adipose tissue and deregulated production and secretion of adi...

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Detalles Bibliográficos
Autores principales: Dong, Ziqi, Gong, Hui, Chen, Yadan, Wu, Hong, Wu, Jun, Deng, Yinghong, Song, Xinmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920035/
https://www.ncbi.nlm.nih.gov/pubmed/29731737
http://dx.doi.org/10.3389/fendo.2018.00167