FoxM1 drives ADAM17/EGFR activation loop to promote mesenchymal transition in glioblastoma

Mesenchymal transition (MES transition) is a hallmark of glioblastoma multiforme (GBM), however, the mechanism regulating the process remains to be elucidated. Here we report that FoxM1 drives ADAM17/EGFR activation loop to promote MES transition in GBM. Firstly, FoxM1 expression was positively asso...

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Detalles Bibliográficos
Autores principales: Zhang, Chunli, Han, Xiu, Xu, Xiao, Zhou, Zhengrong, Chen, Xi, Tang, Yu, Cheng, Jie, Moazzam, Nida Fatima, Liu, Fei, Xu, Jing, Peng, Wanxin, Du, Fengyi, Zhang, Bin, Song, Zhiwen, Zeng, Jian, Gong, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920065/
https://www.ncbi.nlm.nih.gov/pubmed/29700308
http://dx.doi.org/10.1038/s41419-018-0482-4

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