DNA methylation, through DNMT1, has an essential role in the development of gastrointestinal smooth muscle cells and disease

DNA methylation is a key epigenetic modification that can regulate gene expression. Genomic DNA hypomethylation is commonly found in many gastrointestinal (GI) diseases. Dysregulated gene expression in GI smooth muscle cells (GI-SMCs) can lead to motility disorders. However, the consequences of geno...

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Detalles Bibliográficos
Autores principales: Jorgensen, Brian G., Berent, Robyn M., Ha, Se Eun, Horiguchi, Kazuhide, Sasse, Kent C., Becker, Laren S., Ro, Seungil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920081/
https://www.ncbi.nlm.nih.gov/pubmed/29700293
http://dx.doi.org/10.1038/s41419-018-0495-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920081/
https://www.ncbi.nlm.nih.gov/pubmed/29700293
http://dx.doi.org/10.1038/s41419-018-0495-z

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