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DNA methylation, through DNMT1, has an essential role in the development of gastrointestinal smooth muscle cells and disease
DNA methylation is a key epigenetic modification that can regulate gene expression. Genomic DNA hypomethylation is commonly found in many gastrointestinal (GI) diseases. Dysregulated gene expression in GI smooth muscle cells (GI-SMCs) can lead to motility disorders. However, the consequences of geno...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920081/ https://www.ncbi.nlm.nih.gov/pubmed/29700293 http://dx.doi.org/10.1038/s41419-018-0495-z |