Cargando…

Decreased suicide rates in recent antidepressant clinical trials

RATIONALE: The last systematic analysis of suicidality in antidepressant clinical trials submitted for approval by the US Food and Drug Administration was in 2000. Given the attention to suicide and antidepressants in the early 2000s, the authors aimed to evaluate if there have been any changes in s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Arif, Fahl Mar, Kaysee, Gokul, Sagarika, Brown, Walter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920087/ https://www.ncbi.nlm.nih.gov/pubmed/29480436 http://dx.doi.org/10.1007/s00213-018-4856-1

Ejemplares similares

The conundrum of depression clinical trials: one size does not fit all
por: Khan, Arif, et al.
Publicado: (2018)

Does the rising placebo response impact antihypertensive clinical trial outcomes? An analysis of data from the Food and Drug Administration 1990-2016
por: Khan, Arif, et al.
Publicado: (2018)

Magnitude of change with antidepressants and placebo in antidepressant clinical trials using structured, taped and appraised rater interviews (SIGMA-RAPS) compared to trials using traditional semi-structured interviews
por: Khan, Arif, et al.
Publicado: (2014)

Association of Recent Fatherhood With Antidepressant Treatment Initiation Among Men in the United Kingdom
por: Smith, Holly Christina, et al.
Publicado: (2023)

Suicide Rates and Antidepressant Prescribing: A Casual or Causal Relationship?
por: Baune, Bernhard, et al.
Publicado: (2006)

Association of Recent Violence Encounters With Suicidal Ideation Among Adolescents With Depression
por: Wang, Jing, et al.
Publicado: (2023)

Effectiveness of Genotype-Specific Tricyclic Antidepressant Dosing in Patients With Major Depressive Disorder: A Randomized Clinical Trial
por: Vos, Cornelis F., et al.
Publicado: (2023)

Esketamine vs Midazolam in Boosting the Efficacy of Oral Antidepressants for Major Depressive Disorder: A Pilot Randomized Clinical Trial
por: Xiao, Chunfeng, et al.
Publicado: (2023)

Association of Bipolar Disorder Diagnosis With Suicide Mortality Rates in Adolescents in Sweden
por: Andersson, Peter, et al.
Publicado: (2023)

Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals
por: Crawford, Andrew A., et al.
Publicado: (2014)

Association of State Medicaid Expansion Status With Rates of Suicide Among US Adults
por: Patel, Hetal, et al.
Publicado: (2022)

Effect of the Wingman-Connect Upstream Suicide Prevention Program for Air Force Personnel in Training: A Cluster Randomized Clinical Trial
por: Wyman, Peter A., et al.
Publicado: (2020)

Depression, suicidality and antidepressants: A coincidence?
por: Selvaraj, Vithyalakshmi, et al.
Publicado: (2010)

Newer-Generation Antidepressants and Suicide Risk
por: Hayes, Joseph F., et al.
Publicado: (2019)

Use of Quantile Treatment Effects Analysis to Describe Antidepressant Response in Randomized Clinical Trials Submitted to the US Food and Drug Administration: A Secondary Analysis of Pooled Trial Data
por: Meyerson, William U., et al.
Publicado: (2023)

Contextual Factors Associated With County-Level Suicide Rates in the United States, 1999 to 2016
por: Steelesmith, Danielle L., et al.
Publicado: (2019)

Antidepressant-like properties of sarizotan in experimental Parkinsonism
por: Zhang, Xiaoqun, et al.
Publicado: (2011)

Antidepressants and lethal violence in the Netherlands 1994–2008
por: Bouvy, Paul F., et al.
Publicado: (2012)

Assessment of Rates of Suicide Risk Screening and Prevalence of Positive Screening Results Among US Veterans After Implementation of the Veterans Affairs Suicide Risk Identification Strategy
por: Bahraini, Nazanin, et al.
Publicado: (2020)

Antidepressant-Resistant Depression and Antidepressant-Associated Suicidal Behaviour: The Role of Underlying Bipolarity
por: Rihmer, Zoltan, et al.
Publicado: (2011)

Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the 5-HTTLPR
por: Strohmaier, Jana, et al.
Publicado: (2011)

Association of State Social and Environmental Factors With Rates of Self-injury Mortality and Suicide in the United States
por: Rockett, Ian R. H., et al.
Publicado: (2022)

Association Between Means Restriction of Poison and Method-Specific Suicide Rates: A Systematic Review
por: Lim, Jessy S., et al.
Publicado: (2021)

Retroinverso analogs of spadin display increased antidepressant effects
por: Veyssiere, Julie, et al.
Publicado: (2014)

Antidepressant Use and Mortality Among Patients With Hepatocellular Carcinoma
por: Huang, Kuan-Lun, et al.
Publicado: (2023)

Antidepressants Medications and the Relative Risk of Suicide Attempt
por: Mandour, R. A.
Publicado: (2012)

Suicide and Antidepressants: What Current Evidence Indicates
por: Nischal, Anil, et al.
Publicado: (2012)

Antidepressants and Suicide Risk: A Comprehensive Overview
por: Pompili, Maurizio, et al.
Publicado: (2010)

Antidepressants triggering suicidal ideation: An area of concern
por: Rajgadhi, Himali, et al.
Publicado: (2016)

Did the introduction and increased prescribing of antidepressants lead to changes in long-term trends of suicide rates?
por: Amendola, Simone, et al.
Publicado: (2020)

Cost-effectiveness of a Brief Structured Intervention Program Aimed at Preventing Repeat Suicide Attempts Among Those Who Previously Attempted Suicide: A Secondary Analysis of the ASSIP Randomized Clinical Trial
por: Park, A-La, et al.
Publicado: (2018)

A Pilot Study Using Frequent Inpatient Assessments of Suicidal Thinking to Predict Short-Term Postdischarge Suicidal Behavior
por: Wang, Shirley B., et al.
Publicado: (2021)

Effect of Brief Admission to Hospital by Self-referral for Individuals Who Self-harm and Are at Risk of Suicide: A Randomized Clinical Trial
por: Westling, Sofie, et al.
Publicado: (2019)

Exploring the role of drug-metabolising enzymes in antidepressant side effects
por: Hodgson, Karen, et al.
Publicado: (2015)

Association of Linezolid With Risk of Serotonin Syndrome in Patients Receiving Antidepressants
por: Bai, Anthony D., et al.
Publicado: (2022)

Developing an Electroencephalography-Based Model for Predicting Response to Antidepressant Medication
por: Schwartzmann, Benjamin, et al.
Publicado: (2023)

Evaluation of antidepressant activity of vanillin in mice
por: Shoeb, Ahsan, et al.
Publicado: (2013)

Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration
por: Stone, Marc, et al.
Publicado: (2009)

Effectiveness of a Suicide Prevention Module for Adults in Substance Use Disorder Treatment: A Stepped-Wedge Cluster-Randomized Clinical Trial
por: Ries, Richard K., et al.
Publicado: (2022)

Antidepressant Use and Suicide Rates in Adults Aged 75 and Above: A Swedish Nationwide Cohort Study
por: Hedna, Khedidja, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ihmfa2ovi4n11ag5otbinenm9h