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Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells
Curative management of pancreatic adenocarcinoma is limited because this malignancy remains resistant to most chemotherapeutic drugs. Strategies that reverse epigenetic alterations offer a unique opportunity for cancer cell reprogramming, which is valuable for development of new treatments. The aim...
Autores principales: | Gailhouste, Luc, Liew, Lee Chuen, Hatada, Izuho, Nakagama, Hitoshi, Ochiya, Takahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920091/ https://www.ncbi.nlm.nih.gov/pubmed/29700299 http://dx.doi.org/10.1038/s41419-018-0487-z |
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