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Ginkgolic acids induce HepG2 cell death via a combination of apoptosis, autophagy and the mitochondrial pathway

Ginkgolic acids may induce malignant cell death via the B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax)/Bcl-2 apoptosis pathway. Concurrently, apoptosis, autophagy and mitochondrial dysfunction may also be involved in bringing about this endpoint. The anticancer effect of Ginkgolic acids (GAs)...

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Detalles Bibliográficos
Autores principales:	Qi, Qian-Ming, Xue, Yin-Cun, Lv, Jian, Sun, Di, Du, Jian-Xin, Cai, Sheng-Qiang, Li, Yun-He, Gu, Tian-Cun, Wang, Mu-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920365/ https://www.ncbi.nlm.nih.gov/pubmed/29725398 http://dx.doi.org/10.3892/ol.2018.8177

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