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miR-204 reverses temozolomide resistance and inhibits cancer initiating cells phenotypes by degrading FAP-α in glioblastoma

Malignant gliomas are treated with temozolomide (TMZ) at present, but often exhibit resistance to this agent. Cancer-initiating cells (CICs) have been suggested to lead to TMZ resistance. The mechanisms underlying CICs-based TMZ resistance are not fully understood. MicroRNAs (miRNAs) have been demon...

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Detalles Bibliográficos
Autores principales: Yang, Yun-Na, Zhang, Xiang-Hua, Wang, Yan-Ming, Zhang, Xi, Gu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920462/
https://www.ncbi.nlm.nih.gov/pubmed/29725461
http://dx.doi.org/10.3892/ol.2018.8301