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Simultaneous stimulation with tumor necrosis factor-α and transforming growth factor-β1 induces epithelial-mesenchymal transition in colon cancer cells via the NF-κB pathway
Epithelial-mesenchymal transition (EMT) is critical in the progression of numerous types of carcinoma, and endows invasive and metastatic properties upon cancer cells. The tumor microenvironment facilitates tumor metastasis to distant organs. Various signaling pathways contribute to this process. In...
Autores principales: | Li, Yuanfei, Zhu, Guoqiang, Zhai, Huihong, Jia, Junmei, Yang, Wenhui, Li, Xiaoqing, Liu, Lixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920468/ https://www.ncbi.nlm.nih.gov/pubmed/29725419 http://dx.doi.org/10.3892/ol.2018.8230 |
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