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Simultaneous stimulation with tumor necrosis factor-α and transforming growth factor-β1 induces epithelial-mesenchymal transition in colon cancer cells via the NF-κB pathway

Epithelial-mesenchymal transition (EMT) is critical in the progression of numerous types of carcinoma, and endows invasive and metastatic properties upon cancer cells. The tumor microenvironment facilitates tumor metastasis to distant organs. Various signaling pathways contribute to this process. In...

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Detalles Bibliográficos
Autores principales: Li, Yuanfei, Zhu, Guoqiang, Zhai, Huihong, Jia, Junmei, Yang, Wenhui, Li, Xiaoqing, Liu, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920468/
https://www.ncbi.nlm.nih.gov/pubmed/29725419
http://dx.doi.org/10.3892/ol.2018.8230

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