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Clot stability as a determinant of effective factor VIII replacement in hemophilia A

ESSENTIALS: Factor VIII (FVIII) replacement in hemophilia A corrects bleeding due to low thrombin generation. There is uncertainty about the minimal or trough level of FVIII needed for optimal treatment. FVIII improves physical properties of hemophilia clots, including stiffness and permeability. Fi...

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Detalles Bibliográficos
Autores principales: Leong, Lilley, Chernysh, Irina N., Xu, Yifan, Sim, Derek, Nagaswami, Chandrasekaran, de Lange, Zelda, Kosolapova, Sofia, Cuker, Adam, Kauser, Katalin, Weisel, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920517/
https://www.ncbi.nlm.nih.gov/pubmed/29713693
http://dx.doi.org/10.1002/rth2.12034