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Clot stability as a determinant of effective factor VIII replacement in hemophilia A
ESSENTIALS: Factor VIII (FVIII) replacement in hemophilia A corrects bleeding due to low thrombin generation. There is uncertainty about the minimal or trough level of FVIII needed for optimal treatment. FVIII improves physical properties of hemophilia clots, including stiffness and permeability. Fi...
Autores principales: | Leong, Lilley, Chernysh, Irina N., Xu, Yifan, Sim, Derek, Nagaswami, Chandrasekaran, de Lange, Zelda, Kosolapova, Sofia, Cuker, Adam, Kauser, Katalin, Weisel, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920517/ https://www.ncbi.nlm.nih.gov/pubmed/29713693 http://dx.doi.org/10.1002/rth2.12034 |
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