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Reinforced Cytotoxicity of Lymphokine‐activated Killer Cells toward Glioma Cells by Transfection of the Killer Cells with the γ‐Interferon Gene

Lymphokine‐activated killer (LAK) cells generated from peripheral blood lymphocytes incubated with recombinant interleukin‐2 were transfected with the human γ‐interferon (HuIFN‐γ) gene by means of liposomes having a positive charge on their surface. The cells secreted significant amounts of HuIFN‐γ...

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Detalles Bibliográficos
Autores principales: Mizuno, Masaaki, Yoshida, Jun, Takaoka, Toru, Sugita, Kenichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920590/
https://www.ncbi.nlm.nih.gov/pubmed/7537727
http://dx.doi.org/10.1111/j.1349-7006.1995.tb02993.x