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Induction of Erythroid Differentiation by 5‐Fluorouracil in K562 Leukemia Cells

K562 cell line, established from a patient in the blast crisis of chronic myeloid leukemia, expresses high levels of c‐myc and bcr/abl gene products. Exposure of K562 cells to 5‐fluorouracil (5‐FU) resulted in a marked benzidine‐positive erythroid differentiation with concomitant reduction in cell p...

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Detalles Bibliográficos
Autores principales: Yang, Ya‐Wun, Chang, and Yea‐Hueay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920591/
https://www.ncbi.nlm.nih.gov/pubmed/7493914
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03006.x

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