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Low Incidence of Point Mutations in H‐, K‐ and N‐ras Oncogenes and p53 Tumor Suppressor Gene in Renal Cell Carcinoma and Peritoneal Mesothelioma of Wistar Rats Induced by Ferric Nitrilotriacetate

An iron chelate, ferric nitrilotriacetate (Fe‐NTA), induces renal proximal tubular damage, a consequence of iron‐catalyzed free radical reactions, that finally leads to a high incidence of renal cell carcinoma (RCC) in rodents. Previous studies have identified, within 24 h after administration of Fe...

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Detalles Bibliográficos
Autores principales:	Nishiyama, Yasuyuki, Suwa, Hirofumi, Okamoto, Keisei, Fukumoto, Manabu, Hiai, Hiroshi, Toyokuni, Shinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1995
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920660/ https://www.ncbi.nlm.nih.gov/pubmed/8636003 http://dx.doi.org/10.1111/j.1349-7006.1995.tb03308.x

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