Cargando…

Therapy and Imaging of Pancreatic Carcinoma Xenografts with Radioiodine‐labeled Chimeric Monoclonal Antibody A10 and Its Fab Fragment

Recombinant mouse/human chimeric monoclonal antibody A10 (ch‐A10) and its Fab fragment (ch‐Fab) react with carcinoembryonic antigen on various gastrointestinal carcinomas. We performed biodistribution studies with (125)I‐labeled ch‐Al0 and ch‐Fab in an antigen‐positive human pancreatic carcinoma (Bx...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kamigaki, Takashi, Yamamoto, Masahiro, Ohyanagi, Harumasa, Ohya, Masato, Shimazoe, Takao, Kono, Akira, Ohtani, Wataru, Narita, Yuji, Ohkubo, Masahiro, Saitoh, Yoichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1995
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920675/ https://www.ncbi.nlm.nih.gov/pubmed/8636013 http://dx.doi.org/10.1111/j.1349-7006.1995.tb03318.x

Ejemplares similares

Development and Characterization of Chimeric Anti‐carcinoembryonic Antigen Monoclonal Antibodies and Their Fab Fragments
por: Kamigaki, Takashi, et al.
Publicado: (1994)

A Monoclonal Antibody, KM10 Reactive with Human Gastrointestinal Cancer and Its Application for Immunotherapy
por: Ohyanagi, Harumasa, et al.
Publicado: (1988)

Effects of neocarzinostatin-chimeric Fab conjugates on the growth of human pancreatic carcinoma xenografts.
por: Otsuji, E., et al.
Publicado: (1996)

Biodistribution of Neocarzinostatin Conjugated to Chimeric Fab Fragments of the Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Cancer Xenografts
por: Otsuji, Eigo, et al.
Publicado: (1994)

Distribution of neocarzinostatin conjugated to biotinylated chimeric monoclonal antibody Fab fragments after administration of avidin.
por: Otsuji, E., et al.
Publicado: (1996)

Antitumor Effect of DX‐8951, a Novel Camptothecin Analog, on Human Pancreatic Tumor Cells and Their CPT‐11‐resistant Variants Cultured in vitro and Xenografted into Nude Mice
por: Takiguchi, Soichi, et al.
Publicado: (1997)

Molecularly Targeted Therapy of Human Hepatocellular Carcinoma Xenografts with Radio-iodinated Anti-VEGFR2 Murine-Human Chimeric Fab
por: Huang, Jianfei, et al.
Publicado: (2015)

In vivo Efficacy of Neocarzinostatin Coupled with Fab Human/Mouse Chimeric Monoclonal Antibody A7 against Human Colorectal Cancer
por: Yamaguchi, Toshiharu, et al.
Publicado: (1994)

Enhanced Tumor Localization of Radiolabeled Fab Fragments of Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Carcinoma Xenografts
por: Otsuji, Eigo, et al.
Publicado: (1993)

A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro
por: Ding, Guipeng, et al.
Publicado: (2013)

Direct comparison of a radioiodinated intact chimeric anti-CEA MAb with its F(ab')2 fragment in nude mice bearing different human colon cancer xenografts.
por: Vogel, C. A., et al.
Publicado: (1993)

Effects of 16-Week Consumption of Caffeinated and Decaffeinated Instant Coffee on Glucose Metabolism in a Randomized Controlled Trial
por: Ohnaka, Keizo, et al.
Publicado: (2012)

Single chain Fab (scFab) fragment
por: Hust, Michael, et al.
Publicado: (2007)

Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment
por: Kirley, Terence L, et al.
Publicado: (2015)

Experimental Studies on Potentiation of the Antitumor Activity of 5‐Fluorouracil with 3′‐Azido‐3‐deoxythymidine for the Gastric Cancer Cell Line MKN28 in vivo
por: Yasuda, Chikao, et al.
Publicado: (1997)

Defucosylated mouse-dog chimeric anti-HER2 monoclonal antibody exerts antitumor activities in mouse xenograft models of canine tumors
por: Suzuki, Hiroyuki, et al.
Publicado: (2022)

An Antibody Fab Fragment-based Chimeric Antigen Receptor Could Efficiently Eliminate Human Thyroid Cancer Cells
por: Duan, Honghong, et al.
Publicado: (2019)

Soluble Papain to Digest Monoclonal Antibodies; Time and Cost-Effective Method to Obtain Fab Fragment
por: Collins, Matthew, et al.
Publicado: (2022)

Vaccine comprising anti-idiotype antibody conjugate; induces production of neutralizing antibody (human monoclonal antibody, chimeric antibody or FAb, F(Ab′) 2 or Fv fragment) against HIV virus-1
Publicado: (1992)

Production of single chain Fab (scFab) fragments in Bacillus megaterium
por: Jordan, Eva, et al.
Publicado: (2007)

Molecular imaging using an anti-human tissue factor monoclonal antibody in an orthotopic glioma xenograft model
por: Takashima, Hiroki, et al.
Publicado: (2017)

Crystal Structure and Computational Modeling of the Fab Fragment from a Protective Anti-Ricin Monoclonal Antibody
por: Zhao, Zhiyu, et al.
Publicado: (2012)

Mitigation of liquid–liquid phase separation of a monoclonal antibody by mutations of negative charges on the Fab surface
por: Matsuoka, Tatsuji, et al.
Publicado: (2020)

Radioimmunotherapy of colorectal carcinoma xenografts in nude mice with yttrium-90 A33 IgG and Tri-Fab (TFM).
por: Antoniw, P., et al.
Publicado: (1996)

Safety assessment, radioiodination and preclinical evaluation of antinuclear antibody as novel medication for prostate cancer in mouse xenograft model
por: Nguyen, Thu Minh Chau, et al.
Publicado: (2023)

Phage Display Cloning and Characterization of Monoclonal Antibody Genes and Recombinant Fab Fragment against the CD98 Oncoprotein
por: Itoh, Kunihiko, et al.
Publicado: (2001)

Selection and Characterization of YKL-40-Targeting Monoclonal Antibodies from Human Synthetic Fab Phage Display Libraries
por: Kang, Kyungjae, et al.
Publicado: (2020)

Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment
por: Obonai, Toshifumi, et al.
Publicado: (2016)

DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously
por: Beckmann, Roland, et al.
Publicado: (2021)

A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression
por: Warner, Susanne G., et al.
Publicado: (2019)

Fab : the coming revolution on your desktop--from personal computers to personal fabrication
por: Gershenfeld, Neil A.
Publicado: (2005)

Protocol for production and expression of chimeric bovine-human monoclonal antibodies
por: Heydarchi, Behnaz, et al.
Publicado: (2022)

Production and Characterization of Human Monoclonal Antibody Fab Fragments to Vaccinia Virus from a Phage-Display Combinatorial Library()
por: Schmaljohn, Connie, et al.
Publicado: (1999)

Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis
por: Zhu, Lei, et al.
Publicado: (2009)

FabR regulates Salmonella biofilm formation via its direct target FabB
por: Hermans, Kim, et al.
Publicado: (2016)

Disruption of piRNA machinery by deletion of ASZ1/GASZ results in the expression of aberrant chimeric transcripts in gonocytes
por: IKEDA, Shinya, et al.
Publicado: (2022)

False-positive radioiodine uptake after radioiodine treatment in differentiated thyroid cancer
por: Barbaro, Daniele, et al.
Publicado: (2023)

Characterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits
por: Fuchigami, Takeshi, et al.
Publicado: (2015)

The Development of a New Setup for Video-assisted Thoracic Surgery
por: Tsuboi, Masahiro, et al.
Publicado: (1999)

Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (Pb44) protect mice against malarial infection
Publicado: (1980)

Cannot write session to /tmp/vufind_sessions/sess_j7bvh0orbbfqq9brp5k23asuud