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Structural basis of ligand binding modes at the neuropeptide Y Y(1) receptor

Neuropeptide Y (NPY) receptors belong to the G protein-coupled receptor (GPCR) superfamily and play important roles in food intake, anxiety and cancer regulation(1,2). The NPY/Y receptor system has emerged as one of the most complex networks with three peptide ligands (NPY, peptide YY and pancreatic...

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Detalles Bibliográficos
Autores principales: Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brian J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David, Bernhardt, Guenther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C., Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin, Wu, Beili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920736/
https://www.ncbi.nlm.nih.gov/pubmed/29670288
http://dx.doi.org/10.1038/s41586-018-0046-x