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Structural basis of ligand binding modes at the neuropeptide Y Y(1) receptor
Neuropeptide Y (NPY) receptors belong to the G protein-coupled receptor (GPCR) superfamily and play important roles in food intake, anxiety and cancer regulation(1,2). The NPY/Y receptor system has emerged as one of the most complex networks with three peptide ligands (NPY, peptide YY and pancreatic...
Autores principales: | Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brian J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David, Bernhardt, Guenther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C., Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin, Wu, Beili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920736/ https://www.ncbi.nlm.nih.gov/pubmed/29670288 http://dx.doi.org/10.1038/s41586-018-0046-x |
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