Establishment and Characterization of Non‐small Cell Lung Cancer Cell Lines Resistant to Mitomycin C under Aerobic Conditions

To elucidate the mechanisms of acquired resistance to mitomycin C (MMC) in non‐small cell lung cancer (NSCLC), we established two MMC‐resistant NSCLC sublines by continuous exposure to MMC, using PC‐9 as a parent cell line. The sublines, PC‐9/MC2 and PC‐9/MC4, were 6.4‐ and 10‐fold more resistant to...

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Detalles Bibliográficos
Autores principales: Shibata, Kazuhiko, Kasahara, Kazuo, Bando, Takuma, Nakatsumi, Yasuto, Fujimura, Masaki, Tsuruo, Takashi, Matsuda, Tamotsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920845/
https://www.ncbi.nlm.nih.gov/pubmed/7790319
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03079.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920845/
https://www.ncbi.nlm.nih.gov/pubmed/7790319
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03079.x

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