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Enhancement of Ca(2+)‐dependent Endonuclease Activity in L1210 Cells during Apoptosis Induced by 1‐β‐D‐Arabinofuranosylcytosine: Possible Involvement of Activating Factor(s)

Internucleosomal DNA fragmentation and morphological changes in nuclei typical of apoptosis were observed in L1210 cells incubated with 1.0 μg/ml of 1‐β‐D‐arabinofuranosylcytosine (ara‐C). To investigate the mechanisms involved, we examined the activities of endogenous endonucleases in nuclei and cy...

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Detalles Bibliográficos
Autores principales: Takauji, Rumiko, Yoshida, Akira, Iwasaki, Hiromichi, Tohyama, Kaoru, Ueda, Takanori, Nakamura, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920892/
https://www.ncbi.nlm.nih.gov/pubmed/7559086
http://dx.doi.org/10.1111/j.1349-7006.1995.tb02452.x