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Frequent Amplification of the Cyclin E Gene in Human Gastric Carcinomas
We searched for genetic alterations of the cyclin D1 and cyclin E genes in 45 human gastric carcinoma tissues. Expression of cyclin E mRNA and protein was also analyzed in eight of them by Northern and Western blots and immunohistochemical staining. The cyclin E gene was amplified 3–10 fold in seven...
Autores principales: | Akama, Yoshihiko, Yasui, Wataru, Yokozaki, Hiroshi, Kuniyasu, Hiroki, Kitahara, Kenji, Ishikawa, Takenori, Tahara, Eiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920896/ https://www.ncbi.nlm.nih.gov/pubmed/7559076 http://dx.doi.org/10.1111/j.1349-7006.1995.tb02442.x |
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