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Changes in Radiation Sensitivity of Human Osteosarcoma Cells after p53 Introduction

Human osteosarcoma SAOS‐2 cells, which have a deletion in p53 gene, were transfected with plasmid pMSVneop53 containing human p53 cDNA and neomycin‐resistance gene. Three clones (SAOS‐MC10, SAOS‐MC11 and SAOS‐MC43) among 60 clones expressed p53 mRNA. No p53 protein was observed in SAOS‐MC10, while S...

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Detalles Bibliográficos
Autores principales: Miyakoshi, Junji, Yamagishi, Nobuyuki, Ohtsu, Shuji, Takebe, Hiraku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920909/
https://www.ncbi.nlm.nih.gov/pubmed/7559091
http://dx.doi.org/10.1111/j.1349-7006.1995.tb02457.x