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Allelic Loss at the Tuberous Sclerosis (Tsc2) Gene Locus in Spontaneous Uterine Leiomyosarcomas and Pituitary Adenomas in the Eker Rat Model

Hereditary renal carcinomas (RCs) develop in virtually all Eker rats by the age of one year. Investigation of extra‐renal primary tumors co‐occurring in Eker rats late in life (at 2 years) additionally revealed enhanced development of hemangiosarcomas of the spleen, uterine leiomyosarcomas and pitui...

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Detalles Bibliográficos
Autores principales: Kubo, Yoshiaki, Kikuchi, Yasushi, Mitani, Hiroaki, Kobayashi, Etsuko, Kobayashi, Toshiyuki, Hino, Okio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920926/
https://www.ncbi.nlm.nih.gov/pubmed/7591959
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03092.x