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Anti‐tumor Activity of Arginine Deiminase from Mycoplasma arginini and Its Growth‐inhibitory Mechanism

Two kinds of arginine deiminase (AD, EC 3.5.3.6) were purified from cell extracts of Mycoplasma arginini (a‐AD) and Mycoplasma hominis (h‐AD), and their enzymic properties and anti‐tumor activities were compared. The a‐AD enzyme strongly inhibited the growth of mouse hepatoma cell line MH134 in vitr...

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Detalles Bibliográficos
Autores principales: Takaku, Haruo, Matsumoto, Mitsuhiro, Misawa, Satoru, Miyazaki, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920931/
https://www.ncbi.nlm.nih.gov/pubmed/7591961
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03094.x