Cargando…

Antitumor effects of brucine immuno-nanoparticles on hepatocellular carcinoma in vivo

In vitro and in vivo studies have demonstrated that brucine is able to inhibit the proliferation of liver cancer cells and growth of animal tumors, and may be a promising anticancer drug. However, high toxicity, poor water solubility, short half-life, narrow therapeutic window, and similar therapeut...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Jianmin, Yang, Lin, Sheng, Xia, Sa, Zhongqiu, Huang, Tao, Li, Qi, Gao, Kepan, Chen, Qinghua, Ma, Jingwei, Shen, Hebai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920962/ https://www.ncbi.nlm.nih.gov/pubmed/29731843 http://dx.doi.org/10.3892/ol.2018.8168

Ejemplares similares

Anti-tumor effects of brucine immuno-nanoparticles on hepatocellular carcinoma
por: Qin, Jian-Min, et al.
Publicado: (2012)

Stoichiometric and Nonstoichiometric Hydrates of Brucine
por: Braun, Doris E., et al.
Publicado: (2016)

Development, optimization, and evaluation of PEGylated brucine-loaded PLGA nanoparticles
por: Elsewedy, Heba S., et al.
Publicado: (2020)

A Combination of In Silico ADMET Prediction, In Vivo Toxicity Evaluation, and Potential Mechanism Exploration of Brucine and Brucine N-oxide—A Comparative Study
por: Gao, Yan, et al.
Publicado: (2023)

In vitro and in vivo evaluation of novel NGR-modified liposomes containing brucine
por: Li, Shu, et al.
Publicado: (2017)

Effect of Ultrasound-Enhanced Transdermal Drug Delivery Efficiency of Nanoparticles and Brucine
por: Zhang, Nongshan, et al.
Publicado: (2017)

In vitro and in vivo Evaluation of Novel NGR-Modified Liposomes Containing Brucine [Retraction]
Publicado: (2022)

Brucine: A Review of Phytochemistry, Pharmacology, and Toxicology
por: Lu, Lu, et al.
Publicado: (2020)

Pharmacological investigation of brucine anti-ulcer potential
por: Noman, Muhammad, et al.
Publicado: (2022)

Inhibition of Glioblastoma Cell Growth In Vitro and In Vivo by Brucine, a Component of Chinese Medicine
por: Ruijun, Wang, et al.
Publicado: (2015)

Anti-diabetic Activity of Brucine in Streptozotocin-Induced Rats: In Silico, In Vitro, and In Vivo Studies
por: Khan, Naimat Ullah, et al.
Publicado: (2022)

Study of pharmacokinetics and tissue distribution of liposomal brucine for dermal administration
por: Yang, Bai-Can, et al.
Publicado: (2011)

LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4
por: Han, Sheng, et al.
Publicado: (2017)

Effects of brucine on mitochondrial apoptosis and expression of HSP70 in prostate cancer cells
por: Yan, Wei, et al.
Publicado: (2022)

Simultaneous HPTLC determination of strychnine and brucine in strychnos nux-vomica seed
por: Kamal, Abid, et al.
Publicado: (2012)

Hyaluronic acid-coated bovine serum albumin nanoparticles loaded with brucine as selective nanovectors for intra-articular injection
por: Chen, Zhipeng, et al.
Publicado: (2013)

A Novel Brucine Gel Transdermal Delivery System Designed for Anti-Inflammatory and Analgesic Activities
por: Wu, Ping, et al.
Publicado: (2017)

TLC – SPECTROPHOTOMETRIC ANALYSIS OF STRYCHNINE AND BRUCINE FROM THE AYURVEDIC PILLS OF NUX VOMICA
por: Gaitonde, R. V., et al.
Publicado: (1986)

Improved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine
por: Chen, Jun, et al.
Publicado: (2012)

Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway
por: Luo, Wenjuan, et al.
Publicado: (2013)

Brucine inhibits proliferation of glioblastoma cells by targeting the G-quadruplexes in the c-Myb promoter
por: Liu, Qiaochu, et al.
Publicado: (2021)

Quality by Design for Development, Optimization and Characterization of Brucine Ethosomal Gel for Skin Cancer Delivery
por: Ismail, Tamer A., et al.
Publicado: (2021)

ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron
por: Lu, Shan, et al.
Publicado: (2021)

Brucine suppresses proliferation and promotes apoptosis of human cholangiacarcinoma cells via the inhibition of COX2 expression
por: Kang, Qiang, et al.
Publicado: (2023)

Effect of Shodhana (processing) on Kupeelu (Strychnos nux-vomica Linn.) with special reference to strychnine and brucine content
por: Mitra, Swarnendu, et al.
Publicado: (2011)

Brucine Suppresses Vasculogenic Mimicry in Human Triple-Negative Breast Cancer Cell Line MDA-MB-231
por: Xu, Meng-Ran, et al.
Publicado: (2019)

In Vivo and in vitro antitumor activity of tomatine in hepatocellular carcinoma
por: Echeverría, Cesar, et al.
Publicado: (2022)

Quality by Design for Optimizing a Novel Liposomal Jojoba Oil-Based Emulgel to Ameliorate the Anti-Inflammatory Effect of Brucine
por: Abdallah, Marwa H., et al.
Publicado: (2021)

Immuno-Oncotherapeutic Approaches in Advanced Hepatocellular Carcinoma
por: Park, Robin, et al.
Publicado: (2020)

FMO4 shapes immuno‐metabolic reconfiguration in hepatocellular carcinoma
por: Luo, Yan, et al.
Publicado: (2022)

In vitro and in vivo antitumor effect of gefitinib nanoparticles on human lung cancer
por: Ni, Xiao Ling, et al.
Publicado: (2017)

Peritumoral implantation of hydrogel-containing nanoparticles and losartan for enhanced nanoparticle penetration and antitumor effect
por: Shen, Haijun, et al.
Publicado: (2018)

Antitumor Activity of α-Linolenic Acid-Paclitaxel Conjugate Nanoparticles: In vitro and in vivo
por: Xu, Mei-Qi, et al.
Publicado: (2021)

PD‐1 Pathway Inhibitors: Immuno‐Oncology Agents for Restoring Antitumor Immune Responses
por: Medina, Patrick J., et al.
Publicado: (2016)

DR5 mAb-conjugated, DTIC-loaded immuno-nanoparticles effectively and specifically kill malignant melanoma cells in vivo
por: Ding, Baoyue, et al.
Publicado: (2016)

Effects of Brucine on the OPG/RANKL/RANK Signaling Pathway in MDA-MB-231 and MC3T3-E1 Cell Coculture System
por: Wu, Ruixian, et al.
Publicado: (2017)

Delivery of paeonol by nanoparticles enhances its in vitro and in vivo antitumor effects
por: Chen, Cong, et al.
Publicado: (2017)

Lipid Nanoparticle Delivery System for mRNA Encoding B7H3‐redirected Bispecific Antibody Displays Potent Antitumor Effects on Malignant Tumors
por: Huang, Cheng, et al.
Publicado: (2022)

The New Immuno-Oncology-Based Therapies and Their Perspectives in Hepatocellular Carcinoma
por: Merle, Philippe
Publicado: (2021)

In silico trials of combination immuno-radiation for unresectable hepatocellular carcinoma
por: Mendiratta-Lala, Mishal, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ls5gpk31arug5qukeleqkhmta8