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Analysis of Synergism in Hepatocarcinogenesis Based on Preneoplastic Foci Induction by 10 Heterocyclic Amines in the Rat

The effects of simultaneous treatment with 5 or 10 heterocyclic amines at low dose levels on hepatocarcinogenesis in rats were investigated using a medium‐term liver bioassay protocol based on the two‐stage carcinogenesis hypothesis with diethylnitrosamine initiation (200 mg/kg, i.p.). Five carcinog...

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Detalles Bibliográficos
Autores principales: Hasegawa, Ryohei, Yoshimura, Isao, Imaida, Katsumi, Ito, Nobuyuki, Shirai, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921017/
https://www.ncbi.nlm.nih.gov/pubmed/9045941
http://dx.doi.org/10.1111/j.1349-7006.1996.tb03122.x