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Aberrant DNA Methylation on Chromosome 16 Is an Early Event in Hepatocarcinogenesis
In order to clarify the significance of DNA methylation in both earlier and later stages of hepatocarcinogenesis, the DNA methylation state on chromosome 16, on which loss of heterozygosity (LOH) has frequently been detected in human hepatocellular carcinomas (HCCs), was examined. DNA from primary H...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1996
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921026/ https://www.ncbi.nlm.nih.gov/pubmed/9045955 http://dx.doi.org/10.1111/j.1349-7006.1996.tb03135.x |