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Aberrant DNA Methylation on Chromosome 16 Is an Early Event in Hepatocarcinogenesis

In order to clarify the significance of DNA methylation in both earlier and later stages of hepatocarcinogenesis, the DNA methylation state on chromosome 16, on which loss of heterozygosity (LOH) has frequently been detected in human hepatocellular carcinomas (HCCs), was examined. DNA from primary H...

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Detalles Bibliográficos
Autores principales:	Kanai, Yae, Ushijima, Saori, Tsuda, Hitoshi, Sakamoto, Michiie, Sugimura, Takashi, Hirohashi, Setsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1996
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921026/ https://www.ncbi.nlm.nih.gov/pubmed/9045955 http://dx.doi.org/10.1111/j.1349-7006.1996.tb03135.x

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