Relationship between Cell‐killing Efficiency and Number of Platinum Atoms Binding to DNA, RNA, and Protein Molecules in HeLa Cells Treated with cis‐Diamine(glycolato)platinum(II)

HeLa S‐3 cells were treated with (195m)Pt‐radiolabeled cis‐diamine(glycolato)platinum(II) (254‐S) under various conditions, and the relationship between the lethal effect and the numbers of Pt atoms binding to DNA, RNA, and proteins was examined. The mean lethal concentrations for the cells treated...

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Detalles Bibliográficos
Autores principales: Akaboshi, Mitsuhiko, Kawai, Kenichi, Kinashi, Yuko, Masunaga, Shinichiro, Ono, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921063/
https://www.ncbi.nlm.nih.gov/pubmed/8609067
http://dx.doi.org/10.1111/j.1349-7006.1996.tb03156.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921063/
https://www.ncbi.nlm.nih.gov/pubmed/8609067
http://dx.doi.org/10.1111/j.1349-7006.1996.tb03156.x

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