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p53 Gene Deficiency Does Not Enhance Instability of Mouse Minisatellites in Somatic Cells of Normal Tissues
The effect of p53‐deficiency on somatic mutation of minisatellites in normal tissues was examined using p53‐deficient (−/−) mice. In total, 248 mice consisting of three different genotypes, +/+, +/− and −/−, were obtained and DNA from their embryos was probed with two minisatellites, Pc‐1 and Pc‐2....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1996
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921163/ https://www.ncbi.nlm.nih.gov/pubmed/8698618 http://dx.doi.org/10.1111/j.1349-7006.1996.tb00280.x |