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Simultaneous Measurement of Unscheduled and Replicating DNA Synthesis by Means of a New Cell Culture Insert DNA Retention Method: Rapid Induction of Replicating DNA Synthesis in Response to Genotoxic Carcinogens
In order to measure simultaneously replicating DNA synthesis (RDS) and unscheduled DNA synthesis (UDS) in rat hepatocytes responding to exposure to carcinogens, a new method, namely the “cell culture insert DNA retention (CDR)” method, was developed. All CDR procedures for cell culture, digestion of...
Autores principales: | Okumura, Ataru, Tanaka, Takuji, Mori, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921173/ https://www.ncbi.nlm.nih.gov/pubmed/8797886 http://dx.doi.org/10.1111/j.1349-7006.1996.tb02104.x |
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