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Methotrexate remediates spinal cord injury in vivo and in vitro via suppression of endoplasmic reticulum stress-induced apoptosis

It has been suggested that endoplasmic reticulum stress (ERS) may induce apoptosis following spinal cord injury (SCI). Methotrexate (MTX) has been used as a long-term therapy regimen for rheumatoid arthritis. However, it is not clear whether MTX remediates SCI by inhibiting ERS. In the present study...

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Detalles Bibliográficos
Autores principales:	Rong, Fengju, Gao, Xue, Liu, Kexin, Wu, Jintao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921236/ https://www.ncbi.nlm.nih.gov/pubmed/29731818 http://dx.doi.org/10.3892/etm.2018.5973

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