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Regression of Metastatic Liver Tumors in Rats Treated with Angiogenesis Inhibitor TNP‐470: Occurrence of Apoptosis and Necrosis
To clarify the mechanism of the reduction of metastatic liver tumors in rats treated with angiogenesis inhibitor TNP‐470, the death of tumor cells was examined pathologically and ultrastructurally. Liver metastases were developed by intravenous injection of AH‐130 cells. TNP‐470 was given subcutaneo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921286/ https://www.ncbi.nlm.nih.gov/pubmed/9414660 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00318.x |