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Regression of Metastatic Liver Tumors in Rats Treated with Angiogenesis Inhibitor TNP‐470: Occurrence of Apoptosis and Necrosis

To clarify the mechanism of the reduction of metastatic liver tumors in rats treated with angiogenesis inhibitor TNP‐470, the death of tumor cells was examined pathologically and ultrastructurally. Liver metastases were developed by intravenous injection of AH‐130 cells. TNP‐470 was given subcutaneo...

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Detalles Bibliográficos
Autores principales: Ahmed, Motahar H., Aral, Tomio, Konno, Hiroyuki, Nahar, Lutfun, Tanaka, Tatsuro, Izumiyama, Naotaka, Takubo, Kaiyo, Nakamura, Satoshi, Baba, Shozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921286/
https://www.ncbi.nlm.nih.gov/pubmed/9414660
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00318.x