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Combination Therapy with Antibody and Interleukin–2 Gene Transfer against Multidrug–resistant Cancer Cells

In the present study, we examined the effect of intcrlcukin–2 (IL–2) gene transfer into multidrug resistance (MDR) cancer cells on the therapeutic efficacy of MRK16. Human MDR ovarian cancer cells, AD10, were transduced with a bicistronic IL–2 retrovirus, Ha–IL2–IRES–Neo. The G418resistant populatio...

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Detalles Bibliográficos
Autores principales:	Shinohara, Tsutomu, Sugimoto, Yoshikazu, Sato, Shigeo, Sone, Saburo, Tsuruo, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921314/ https://www.ncbi.nlm.nih.gov/pubmed/9439686 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00335.x

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