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Inhibitory Effect of NS‐398, a Selective Cyclooxygenase‐2 Inhibitor, on Azoxymethane‐induced Aberrant Crypt Foci in Colon Carcinogenesis of F344 Rats

Prostaglandin E(2), which is produced by cyclooxygenase (COX) during arachidonic acid metabolism, is considered to be related to colon Carcinogenesis. Therefore, the effect of NS‐398 (N‐(2‐cyclohexyl‐oxy‐4‐nitrophenyl)methanesulfonamide), a COX‐2 inhibitor, was examined in azoxymethane (AOM)‐induced...

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Detalles Bibliográficos
Autores principales:	Yoshimi, Naoki, Kawabata, Kunihiro, Hara, Akira, Matsunaga, Kengo, Yamada, Yasuhiro, Mori, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921322/ https://www.ncbi.nlm.nih.gov/pubmed/9439679 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00328.x

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