Cargando…

Direct Intratumoral Gene Transfer of the Herpes Simplex Virus Thymidine Kinase Gene with DNA‐liposome Complexes: Growth Inhibition of Tumors and Lack of Localization in Normal Tissues

To constitute the site‐specific expression of the herpes simplex virus thymidine‐kinase (HSV‐TK) gene in tumor cells, we have assessed the promoter function of the simian virus 40 (SV40) promoter and the 5’flanking region of c‐erbB‐2 gene using a luciferase‐expressing reporter plasmid. After the tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takakuwa, Koicni, Fujita, Kazuyuki, Kikuchi, Akira, Sugaya, Susumu, Yahata, Tetsuro, Aida, Hiroshi, Kurabayashi, Takumi, Hasegawa, Isao, Tanaka, Kenichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921354/ https://www.ncbi.nlm.nih.gov/pubmed/9119745 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00362.x

Ejemplares similares

Orthotopic hepatic cancer: radiofrequency hyperthermia-enhanced intratumoral herpes simplex virus-thymidine kinase gene therapy
por: Xiong, Fu, et al.
Publicado: (2017)

3'-Amino thymidine affinity matrix for the purification of herpes simplex virus thymidine kinase.
por: Tung, P. P., et al.
Publicado: (1996)

In vivo Retrovirus‐mediated Herpes Simplex Virus Thymidine Kinase Gene Therapy Approach for Adult T Cell Leukemia in a Rat Model
por: Murata, Ken, et al.
Publicado: (1997)

Ultrasound-targeted microbubble destruction mediated herpes simplex virus-thymidine kinase gene treats hepatoma in mice
por: Zhou, Shiji, et al.
Publicado: (2010)

Suicide gene therapy for hepatocellular carcinoma cells by survivin promoter-driven expression of the herpes simplex virus thymidine kinase gene
por: QU, LILI, et al.
Publicado: (2013)

Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy combined with ganciclovir induces hepatoma cell apoptosis
por: Zhang, Haitao, et al.
Publicado: (2019)

Variant Analysis of the Thymidine Kinase and DNA Polymerase Genes of Herpes Simplex Virus in Korea: Frequency of Acyclovir Resistance Mutations
por: Hyun, Jungwon, et al.
Publicado: (2023)

The Role of Herpes Simplex Virus-1 Thymidine Kinase Alanine 168 in Substrate Specificity
por: Willmon, Candice L, et al.
Publicado: (2008)

Modulation of the Intratumoral Immune Landscape by Oncolytic Herpes Simplex Virus Virotherapy
por: Yin, Jie, et al.
Publicado: (2017)

Engineering and Characterization of Oncolytic Vaccinia Virus Expressing Truncated Herpes Simplex Virus Thymidine Kinase
por: Islam, S. M. Bakhtiar Ul, et al.
Publicado: (2020)

Targeting of Herpes Simplex Virus 1 Thymidine Kinase Gene Sequences into the OCT4 Locus of Human Induced Pluripotent Stem Cells
por: Ou, Wu, et al.
Publicado: (2013)

Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells
por: Iwasawa, Chizuru, et al.
Publicado: (2019)

Case report: Stem cell-based suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene reduces tumor progression in multifocal glioblastoma
por: Oraee-Yazdani, Saeed, et al.
Publicado: (2023)

Tanshinone IIA Increases the Bystander Effect of Herpes Simplex Virus Thymidine Kinase/Ganciclovir Gene Therapy via Enhanced Gap Junctional Intercellular Communication
por: Xiao, Jianyong, et al.
Publicado: (2013)

Adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent high-grade glioma
por: Ji, Nan, et al.
Publicado: (2015)

Optimizing fluorescent protein expression for quantitative fluorescence microscopy and spectroscopy using herpes simplex thymidine kinase promoter sequences
por: Ali, Rizwan, et al.
Publicado: (2018)

Association between sensitivity of viral thymidine kinase-associated acyclovir-resistant herpes simplex virus type 1 and virulence
por: Omura, Natsumi, et al.
Publicado: (2017)

Neural Progenitor Cells Expressing Herpes Simplex Virus-Thymidine Kinase for Ablation Have Differential Chemosensitivity to Brivudine and Ganciclovir
por: Lou, Zijian, et al.
Publicado: (2021)

Improving the Safety of Mesenchymal Stem Cell-Based Ex Vivo Therapy Using Herpes Simplex Virus Thymidine Kinase
por: Bashyal, Narayan, et al.
Publicado: (2022)

Synthesis and Biological Evaluation of a New Acyclic Pyrimidine Derivative as a Probe for Imaging Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression
por: Meščić, Andrijana, et al.
Publicado: (2013)

Expression of Herpes Simplex Virus Thymidine Kinase/Ganciclovir by RNA Trans-Splicing Induces Selective Killing of HIV-Producing Cells
por: Ingemarsdotter, Carin K., et al.
Publicado: (2017)

A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivo imaging of gene therapy in malignant glioma
por: Söling, Ariane, et al.
Publicado: (2004)

Adeno‐associated Virus Vector Containing the Herpes Simplex Virus Thymidine Kinase Gene Causes Complete Regression of Intracerebrally Implanted Human Gliomas in Mice, in Conjunction with Ganciclovir Administration
por: Mizuno, Masaaki, et al.
Publicado: (1998)

Inhibitory effects of the ultrasound-targeted microbubble destruction-mediated herpes simplex virus-thymidine kinase/ganciclovir system on ovarian cancer in mice
por: ZHOU, XIAN-LONG, et al.
Publicado: (2014)

Human telomerase reverse-transcriptase promoter-controlled and herpes simplex virus thymidine kinase-armed adenoviruses for renal cell carcinoma treatment
por: Tian, Dawei, et al.
Publicado: (2013)

Gene editing and elimination of latent herpes simplex virus in vivo
por: Aubert, Martine, et al.
Publicado: (2020)

Efficacy and safety of dendrimer nanoparticles with coexpression of tumor necrosis factor-α and herpes simplex virus thymidine kinase in gene radiotherapy of the human uveal melanoma OCM-1 cell line
por: Wang, Yingchih, et al.
Publicado: (2013)

Vesicular Stomatitis Virus G Glycoprotein and ATRA Enhanced Bystander Killing of Chemoresistant Leukemic Cells by Herpes Simplex Virus Thymidine Kinase/Ganciclovir
por: Hu, Chenxi, et al.
Publicado: (2014)

A Herpes Simplex Virus Thymidine Kinase-Induced Mouse Model of Hepatocellular Carcinoma Associated with Up-Regulated Immune-Inflammatory-Related Signals
por: Gong, Zhijuan, et al.
Publicado: (2018)

Dual-modality imaging demonstrates the enhanced antitumoral effect of herpes simplex virus-thymidine kinase/ganciclovir plus gemcitabine combination therapy on cholangiocarcinoma
por: WANG, JIANFENG, et al.
Publicado: (2016)

Engineering and Preclinical Evaluation of Western Reserve Oncolytic Vaccinia Virus Expressing A167Y Mutant Herpes Simplex Virus Thymidine Kinase
por: Islam, S. M. Bakhtiar UL, et al.
Publicado: (2020)

Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System
por: Artusi, Sara, et al.
Publicado: (2018)

Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis
por: Abdelmagid, Nada, et al.
Publicado: (2016)

Liposome-Mediated Herpes Simplex Virus Uptake Is Glycoprotein-D Receptor-Independent but Requires Heparan Sulfate
por: Burnham, Lorrie A., et al.
Publicado: (2016)

C-5 Hydroxyethyl and Hydroxypropyl Acyclonucleosides as Substrates for Thymidine Kinase of Herpes Simplex Virus Type 1 (HSV-1 TK): Syntheses and Biological Evaluation
por: Meščić, Andrijana, et al.
Publicado: (2013)

Herpes Simplex and Pseudorabies Viruses
por: Hierholzer, Walter J.
Publicado: (1970)

Treatment of Herpes Simplex Encephalitis
por: Illis, L. S., et al.
Publicado: (1972)

Fulminating herpes simplex hepatitis
por: Ahmed, Raheel, et al.
Publicado: (2022)

The interaction of Herpes Simplex Virus with murine lymphocytes. I. Mitogenic properties of herpes simplex virus
Publicado: (1977)

A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
por: Uyar, Olus, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ssg7p0640tio19fpebpm2oupuv