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Altered Expression of γ‐Glutamylcysteine Synthetase, Metallothionein and Topoisomerase I or II during Acquisition of Drug Resistance to Cisplatin in Human Ovarian Cancer Cells

This study was designed to elucidate the mechanisms of cisplatin (CDDP) resistance using two human ovarian cancer cell lines, KF and TYK, and two CDDP‐resistant lines, KFr and TYK/R, derived from the former lines. KFr and TYK/R showed about 3‐fold higher resistance to the cytotoxic effects of CDDP t...

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Detalles Bibliográficos
Autores principales:	Kikuchi, Yoshihiro, Hirata, Junko, Yamamoto, Kenji, Ishii, Kenji, Kita, Tsunekazu, Kudoh, Kazuya, Tode, Takehiko, Nagata, Ichiro, Taniguchi, Ken, Kuwano, Michihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921366/ https://www.ncbi.nlm.nih.gov/pubmed/9119751 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00368.x

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