Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review

BACKGROUND: Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding. CASE PRESENTATION: We experienced an elderly woman who pr...

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Autores principales: Miyake, Keita, Hara, Takashi, Oshima, Etsuko, Kawada, Kiyohiro, Ishizu, Hideki, Yamauchi, Yuko, Satoh, Katsuya, Kitamoto, Tetsuyuki, Takenoshita, Shintaro, Terada, Seishi, Yamada, Norihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921414/
https://www.ncbi.nlm.nih.gov/pubmed/29699515
http://dx.doi.org/10.1186/s12883-018-1055-y
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author Miyake, Keita
Hara, Takashi
Oshima, Etsuko
Kawada, Kiyohiro
Ishizu, Hideki
Yamauchi, Yuko
Satoh, Katsuya
Kitamoto, Tetsuyuki
Takenoshita, Shintaro
Terada, Seishi
Yamada, Norihito
author_facet Miyake, Keita
Hara, Takashi
Oshima, Etsuko
Kawada, Kiyohiro
Ishizu, Hideki
Yamauchi, Yuko
Satoh, Katsuya
Kitamoto, Tetsuyuki
Takenoshita, Shintaro
Terada, Seishi
Yamada, Norihito
author_sort Miyake, Keita
collection PubMed
description BACKGROUND: Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding. CASE PRESENTATION: We experienced an elderly woman who presented initially with status epilepticus following repeated partial seizures in the course of Alzheimer disease (AD) dementia. Anti-convulsive therapy had no effect. Autopsy revealed definite CJD with AD pathology. COCLUSIONS: This is the first reported CJD case presenting with status epilepticus in the course of AD dementia.
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spelling pubmed-59214142018-05-01 Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review Miyake, Keita Hara, Takashi Oshima, Etsuko Kawada, Kiyohiro Ishizu, Hideki Yamauchi, Yuko Satoh, Katsuya Kitamoto, Tetsuyuki Takenoshita, Shintaro Terada, Seishi Yamada, Norihito BMC Neurol Case Report BACKGROUND: Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding. CASE PRESENTATION: We experienced an elderly woman who presented initially with status epilepticus following repeated partial seizures in the course of Alzheimer disease (AD) dementia. Anti-convulsive therapy had no effect. Autopsy revealed definite CJD with AD pathology. COCLUSIONS: This is the first reported CJD case presenting with status epilepticus in the course of AD dementia. BioMed Central 2018-04-25 /pmc/articles/PMC5921414/ /pubmed/29699515 http://dx.doi.org/10.1186/s12883-018-1055-y Text en © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Miyake, Keita
Hara, Takashi
Oshima, Etsuko
Kawada, Kiyohiro
Ishizu, Hideki
Yamauchi, Yuko
Satoh, Katsuya
Kitamoto, Tetsuyuki
Takenoshita, Shintaro
Terada, Seishi
Yamada, Norihito
Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
title Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
title_full Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
title_fullStr Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
title_full_unstemmed Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
title_short Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
title_sort creutzfeldt-jakob disease with alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921414/
https://www.ncbi.nlm.nih.gov/pubmed/29699515
http://dx.doi.org/10.1186/s12883-018-1055-y
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