Rare Occurrence of ras and p53 Gene Mutations in Mouse Stomach Tumors Induced by N–Methyl–N–nitrosourea

The incidence of point mutations of H–, K– and N–ras and p53 oncogenes in male BALB/c mouse stomach tumors induced with A(r)–methyl–A(r)–nitrosourea (MNU) was examined by direct sequencing and PCR single–strand conformation polymorphism (PCR–SSCP). A mutation of GGT to AGT at K–ras codon 12 was foun...

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Detalles Bibliográficos
Autores principales: Furihata, Chie, Tatematsu, Masae, Saito, Masae, Ishida, Shizuka, Nakanishi, Hayao, Inada, Ken‐ichi, Tei, Hajime, Hattori, Masahira, Ito, Takashi, Sakaki, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921434/
https://www.ncbi.nlm.nih.gov/pubmed/9197527
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00390.x

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