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Cell‐killing Efficiency and Number of Platinum Atoms Binding to DNA, RNA and Protein Molecules of HeLa Cells Treated with Combinations of trans‐Diammedichloroplatinum(II) and Hyperthermia

The effect of hyperthermia on the cell‐killing efficiency of Pt atoms binding to DNA, RNA and protein molecules was examined. HeLa S‐3 cells were treated with (195m)Pt‐radiolabeled trans‐diaminedichloro‐platinum(II) (TDDP) for 60 min at various temperatures, and the relationship between the lethal e...

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Detalles Bibliográficos
Autores principales:	Akaboshi, Mitsuhiko, Kawai, Kenichi, Kinashi, Yuko, Masunaga, Shinichiro, Ono, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921455/ https://www.ncbi.nlm.nih.gov/pubmed/9247608 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00410.x

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