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A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae

Macroautophagy (hereafter autophagy) is a cellular recycling pathway essential for cell survival during nutrient deprivation that culminates in the degradation of cargo within the vacuole in yeast and the lysosome in mammals, followed by efflux of the resultant macromolecules back into the cytosol....

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Detalles Bibliográficos
Autores principales: Parzych, Katherine R., Ariosa, Aileen, Mari, Muriel, Klionsky, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921575/
https://www.ncbi.nlm.nih.gov/pubmed/29514932
http://dx.doi.org/10.1091/mbc.E17-08-0516