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C3G dynamically associates with nuclear speckles and regulates mRNA splicing

C3G (Crk SH3 domain binding guanine nucleotide releasing factor) (Rap guanine nucleotide exchange factor 1), essential for mammalian embryonic development, is ubiquitously expressed and undergoes regulated nucleocytoplasmic exchange. Here we show that C3G localizes to SC35-positive nuclear speckles...

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Detalles Bibliográficos
Autores principales: Shakyawar, Dhruv Kumar, Muralikrishna, Bhattiprolu, Radha, Vegesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921577/
https://www.ncbi.nlm.nih.gov/pubmed/29496966
http://dx.doi.org/10.1091/mbc.E17-07-0442