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Infrequent Mutations in the PTEN/MMAC1 Gene among Primary Breast Cancers

Recently PTEN/MMAC1, a candidate tumor suppressor gene, was isolated from chromosome 10q23‐24 and somatic mutations of this gene were detected in several malignancies including brain, prostate, and breast tumors. To investigate further the potential role of this gene in mammary carcinogenesis, we ex...

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Detalles Bibliográficos
Autores principales: Ueda, Kazuki, Nishijima, Misae, Inui, Hiroki, Watatani, Masahiro, Yayoi, Eiji, Okamura, Jun, Yasutomi, Masayuki, Nakamura, Yusuke, Miyoshi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921581/
https://www.ncbi.nlm.nih.gov/pubmed/9510470
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00473.x