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Multiplex Mutation Screening of the BRCA1 Gene in 1000 Japanese Breast Cancers
To detect BRCA1 mutations in Japanese breast cancer patients, we screened 1,000 unselected primary cancers for mutations in exon 11, which accounts for 61% of the entire BRCA1 coding sequence. Using a method based on multiplex single‐strand conformational polymorphism (SSCP) analysis of multiple res...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921586/ https://www.ncbi.nlm.nih.gov/pubmed/9510469 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00472.x |