Cargando…

Multiplex Mutation Screening of the BRCA1 Gene in 1000 Japanese Breast Cancers

To detect BRCA1 mutations in Japanese breast cancer patients, we screened 1,000 unselected primary cancers for mutations in exon 11, which accounts for 61% of the entire BRCA1 coding sequence. Using a method based on multiplex single‐strand conformational polymorphism (SSCP) analysis of multiple res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Emi, Mitsuru, Matsushima, Mieko, Katagiri, Toyomasa, Yoshimoto, Masataka, Kasumi, Fujio, Yokota, Takashi, Nakata, Tomoko, Miki, Yoshio, Nakamura, Yusuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921586/ https://www.ncbi.nlm.nih.gov/pubmed/9510469 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00472.x

Ejemplares similares

Mapping of a Breast Cancer Tumor Suppressor Gene Locus to a 4‐cM Interval on Chromosome 18q21
por: Yokota, Takashi, et al.
Publicado: (1997)

Infrequent Mutation of the H‐Cadherin Gene on Chromosome 16q24 in Human Breast Cancers
por: Miki, Yoshio, et al.
Publicado: (1997)

Genome-Wide Association Study of Breast Cancer in the Japanese Population
por: Low, Siew-Kee, et al.
Publicado: (2013)

An open cohort study of bone metastasis incidence following surgery in breast cancer patients
por: Koizumi, Mitsuru, et al.
Publicado: (2010)

Post-operative breast cancer patients diagnosed with skeletal metastasis without bone pain had fewer skeletal-related events and deaths than those with bone pain
por: Koizumi, Mitsuru, et al.
Publicado: (2010)

Association of Allelic Losses at 3p25.1, 13q12, or 17p13.3 with Poor Prognosis in Breast Cancers with Lymph Node Metastasis
por: Haga, Shunsuke, et al.
Publicado: (2001)

Mapping of Target Regions of Allelic Loss in Primary Breast Cancers to 1‐cM Intervals on Genomic Contigs at 6q21 and 6q25.3
por: Utada, Yoshihito, et al.
Publicado: (2000)

Frequent Allelic Loss at 7p14‐15 Associated with Aggressive Histologic Types of Breast Cancer
por: Kurose, Keisuke, et al.
Publicado: (1998)

Allelic Loss on Chromosome 9q Is Associated with Lymph Node Metastasis of Primary Breast Cancer
por: Minobe, Kaori, et al.
Publicado: (1998)

Functional genomics for breast cancer drug target discovery
por: Yoshimaru, Tetsuro, et al.
Publicado: (2021)

Unexpected increase in the bone marrow toxicity of mitomycin C (MMC)
por: Yoshimoto, Masataka, et al.
Publicado: (2001)

Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls
por: Momozawa, Yukihide, et al.
Publicado: (2018)

Lack of impact of the ALDH2 rs671 variant on breast cancer development in Japanese BRCA1/2‐mutation carriers
por: Mori, Tomoharu, et al.
Publicado: (2022)

The prediction models for postoperative overall survival and disease‐free survival in patients with breast cancer
por: Shigemizu, Daichi, et al.
Publicado: (2017)

Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family
por: Lin, Meng-Lay, et al.
Publicado: (2007)

Association of genetic alterations on chromosome 17 and loss of hormone receptors in breast cancer.
por: Ito, I., et al.
Publicado: (1995)

Federated analysis of BRCA1 and BRCA2 variation in a Japanese cohort
por: Casaletto, James, et al.
Publicado: (2022)

BRCA1/BRCA2 mutations in Japanese women with ductal carcinoma in situ
por: Liu, Yan, et al.
Publicado: (2019)

Overexpression of C16orf74 is involved in aggressive pancreatic cancers
por: Nakamura, Toru, et al.
Publicado: (2016)

Localization of a breast cancer tumour-suppressor gene to a 3-cM interval within chromosomal region 16q22.
por: Iida, A., et al.
Publicado: (1997)

Mutation status of RAD51C,PALB2 and BRIP1 in 100 Japanese familial breast cancer cases without BRCA1 and BRCA2 mutations
por: Sato, Katsutoshi, et al.
Publicado: (2017)

Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells()()
por: Deng, Boya, et al.
Publicado: (2018)

FZD10‐targeted α‐radioimmunotherapy with (225)Ac‐labeled OTSA101 achieves complete remission in a synovial sarcoma model
por: Sudo, Hitomi, et al.
Publicado: (2021)

Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population
por: Low, Siew-Kee, et al.
Publicado: (2019)

Prevalence of disease-causing genes in Japanese patients with BRCA1/2-wildtype hereditary breast and ovarian cancer syndrome
por: Kaneyasu, Tomoko, et al.
Publicado: (2020)

Clinicopathological features, genetic alterations, and BRCA1 promoter methylation in Japanese male patients with breast cancer
por: Shimomura, Akihiko, et al.
Publicado: (2022)

Nitric oxide is associated with fracture risk in Japanese women
por: Shiraki, Masataka, et al.
Publicado: (2023)

Occupational Factors and Problem Drinking among a Japanese Working Population
por: HASEGAWA, Takuya, et al.
Publicado: (2013)

Prediction of Sensitivity to STI571 among Chronic Myeloid Leukemia Patients by Genome‐wide cDNA Microarray Analysis
por: Kaneta, Yasuyuki, et al.
Publicado: (2002)

BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein
por: Malik, Sadiya, et al.
Publicado: (2016)

Comparison of two multiplexed technologies for profiling >1,000 serum proteins that may associate with tumor burden
por: Ren, Annie, et al.
Publicado: (2021)

Risk prediction for metastasis of clear cell renal cell carcinoma using digital multiplex ligation‐dependent probe amplification
por: Yoshikawa, Yoshie, et al.
Publicado: (2021)

Evaluation of the Effects of a Combination of Japanese Honey and Hydrocolloid Dressing on Cutaneous Wound Healing in Male Mice
por: Mukai, Kanae, et al.
Publicado: (2015)

Mutational Analysis of Mismatch Repair Genes, hMLH1 and hMSH2, in Sporadic Endometrial Carcinomas with Microsatellite Instability
por: Kobayashi, Kanji, et al.
Publicado: (1996)

1000 successes as CDDIS reaches 1000 published papers!
por: Melino, G
Publicado: (2014)

Young Japanese College Students with Dysmenorrhea Have High Frequency of Irregular Menstruation and Premenstrual Symptoms
por: Fujiwara, Tomoko, et al.
Publicado: (2007)

Detection of BRCA1 and BRCA2 germline mutations in Japanese population using next-generation sequencing
por: Hirotsu, Yosuke, et al.
Publicado: (2015)

1000 signs /
Publicado: (2004)

Association of food access and neighbor relationships with diet and underweight among community-dwelling older Japanese
por: Nakamura, Hideko, et al.
Publicado: (2017)

Low carbohydrate diet-based intervention for obstructive sleep apnea and primary hypothyroidism in an obese Japanese man
por: Tokuchi, Yoshio, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bqojb6akghkmji4angqb10jvpi