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In vivo Efficacy and Tumor‐selective Metabolism of Amrubicin to Its Active Metabolite
The tissue distribution of a novel antitumor anthracycline antibiotic, amrubicin, was studied using seven human tumor xenografts implanted into nude mice, in order to identify the principal factors determining its therapeutic efficacy. We found a good correlation between the level of the metabolite...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1998
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921694/ https://www.ncbi.nlm.nih.gov/pubmed/9849585 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00496.x |