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Cytotoxicity of Amrubicin, a Novel 9‐Aminoanthracycline, and Its Active Metabolite Amrubicinol on Human Tumor Cells

Amrubicin, a completely synthetic 9‐aminoanthracycline derivative, was previously shown to have potent antitumor activities against various human tumor xenografts. In this study, the in vitro activities of amrubicin and its major metabolite, amrubicinol, were examined using 17 human tumor cell lines...

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Detalles Bibliográficos
Autores principales: Yamaoka, Takashi, Hanada, Mituharu, Ichii, Shinji, Morisada, Shinya, Noguchi, Toshihiro, Yanagi, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921698/
https://www.ncbi.nlm.nih.gov/pubmed/9849587
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00498.x