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Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer’s disease mice
BACKGROUND: There is increasing interest in whether anesthetic agents affect the risk or progression of Alzheimer’s disease (AD). To mitigate many of the methodological issues encountered in human retrospective cohort studies we have used a transgenic model of AD to investigate the effect of propofo...
Autores principales: | Woodhouse, Adele, Fernandez-Martos, Carmen Maria, Atkinson, Rachel Alice Kathryn, Hanson, Kelsey Anne, Collins, Jessica Marie, O’Mara, Aidan Ryan, Terblanche, Nico, Skinner, Marcus Welby, Vickers, James Clement, King, Anna Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921792/ https://www.ncbi.nlm.nih.gov/pubmed/29699479 http://dx.doi.org/10.1186/s12871-018-0509-5 |
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