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p53 Gene Mutation and Loss of Heterozygosity of Chromosome 11 in Methylcholanthrene‐induced Mouse Sarcomas

Mutations of the p53 tumor suppressor gene are the most prevalent genetic alteration observed in a wide variety of human cancers. In this study we examined 63 methylcholanthrene (MCA)‐induced sarcomas from C57BL/6N×C3H/HeN F(1) (BCF(1)) or C3H/HeN×C57BL/6N F(1) (CBF(1)) mice for p53 gene mutations a...

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Detalles Bibliográficos
Autores principales:	Shimokado, Kiyoshi, Watanabe, Hiroshi, Sumii, Masaharu, Miyagawa, Kiyoshi, Kamiya, Kenji, Dohi, Kiyohiko, Niwa, Ohtsura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921802/ https://www.ncbi.nlm.nih.gov/pubmed/9600120 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00558.x

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