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Novel Point Mutations and Allele Loss at the RET Locus in Sporadic Medullary Thyroid Carcinomas

Germline mutations in the RET proto‐oncogene have been shown to be the underlying cause of multiple endocrine neoplasia type 2 (MEN 2A and 2B) and familial medullary thyroid carcinoma (FMTC). Some cases of sporadic medullary thyroid carcinoma (sporadic MTC) are reported to have specific codon 918, 8...

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Detalles Bibliográficos
Autores principales: Uchino, Shinya, Noguchi, Shiro, Adachi, Mitsuo, Sato, Mari, Yamashita, Hiroyuki, Watanabe, Shin, Murakami, Tsukasa, Toda, Masakatsu, Murakami, Nobuo, Yamashita, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921821/
https://www.ncbi.nlm.nih.gov/pubmed/9617347
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00579.x